That could really be a lot of things.
Most likely is a wrong memory stepping, especially if you overclocked your PC, but it could also be damaged memory-chips, which you can both check with memtest86, as MaXMhZ suggested.
You should also disable all "spread xy" in the BIOS-options, cause some components don't take this well on fast machines (especially overclocked) and you should ensure the memory is cooled. Most people with watercooling, for example, always forget that there are more components on a mainboard that need cooling than just the CPU and the southbridge.
CPU BurnIn or CoreTemp are both very nice tools to check if your processor is cooled good enough for idle and under stress.
With CPU-Z you can also check the current frequency-settings against the original values suitable for the used CPU and memory.
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