@JG53Frankyboy: canceled the anthropomorphe filter for my Geforce GTX 460 but still the same problems.
@huckster: When i started the german campaign i couldn't even raise my gear after take of (109). Also there is no "Screen response" when i press "G" on the Keyboard like it is if i hit i.g. "I" it shows "Engine Start". Strangely Spitfire and Hurrican work just fine.
BTW, forgot to mention i'm on basic engine management, don't know if it makes a difference in that case.
Anyway, thanks for trying to help guys, i very much appreciate that!
Maybe one of the next patches would solve this problem....