Crashed my machine

[wobblybob54]

Running Quad Core 3.4, Vista 64, 4gb ram, 9800x2 card. Loaded game and EU patch went to launch and it came up with following
Runtime error 9at 328.155)Access violation at address 76D21Fc4 Read only address 030D8000.
Drivers upto date on my card by the way. Thrown back to desktop, unable to uninstall - same message came up. Deleted in the end, I know you're not supposed to. Then tried to play World in Conflict: complete Edition and same message came up, in fact tried a few more games which did the same. Had to do a system restore to get rid of the screen. Never had problems like this before. Any thoughts?? Cheers