I completely agree with Ryastar here, who is right on. Pygmy and Helplessness can be VERY powerful.
As an example, consider fighting ArchDemons on lava terrain, which you have to do for some of the hardest fights (like Baal, who has a huge stack of them). Their Defense is already 78 by that point, before the Hero bonus. A 60% reduction of Defense from Helplessless reduces its Defense by 47, which means that your units now do 256% of their damage without Helplessness cast against Archdemons! (Including the enemy Hero's defense makes this even bigger). So if you're fighting 20 Archdemons, where you could only kill 8 beforehand, giving them a chance to inflict some major pain on their turn, cast Helplessness and watch the whole stack go down. That's how good Helplessness can be. (but of course it's best with high defense units)
Weakness is rather useless in contrast, since you can be much more effective at minimizing damage received by using careful tactics and by simply killing their units first, i.e. with Pygmy and Helplessness.
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