I don't know if using JSGME to install & test patches and/or mods has been discussed in this forum before, but this little utility makes it very easy to install/uninstall patches or mods for testing and/or keeping.
I've been successfully using this utility with CloD and various other Games, being sure to always have a clean basic game installation 'beneath' the mods/patches to return to, in case something goes wrong.
JSGME is no longer being further developed, but you can find the most recent version here:
www.gamefront.com/files/21681483/JSGME.7z
Believe me, it makes testing and using patches and mods soo much easier, especially when adding up several mods on top of each other, ie. making a 'mod soup'

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Cheers
Uffe