@ silvirus
Try reinstalling all (4?) programs from the /redist/ folder, video drivers (try earlier versions for your card), chipset drivers. Your system should run it with Win7-64 at least.
Try set default clocks if you overclocked anything. Make sure your PSU is not dying and provides adecuate power to your video card. CloD loads your card at 100%.
Try changing conf.ini to run in a window for testing.
Disable Steam ingame overlay in Steam and change Steam hotkey fror overlay to something else, IIRC 2 keys should be fine like Shift-Tab or Ctrl-Tab. Default key may cause crashes.
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