Hmm, a new game should run fine with the No Dustclouds mod. Bad/incompatible saves don't even load, you usually get a "save file is corrupt" error, so I doubt it's that mod. Strange. We could try looking at what exactly is causing your crash; open your game folder and find a file named LOGfile.txt and post it here (get it immediately after a crash because the game overwrites it every time you start).