One of the following may work for you:
Right-click on the game's executible file and select "run as administrator"
Right-Click on the game's executible file and select "Properties" > "Security" and click the "Edit" button. Now highlight each of the users and check the "Full Control" box if it's not already checked.
If you're using the OS compatibility feature, try switching to Vista from XP or visa versa.
If the aforementioned procedures don't work for you, then forget the game, crack open a beer and just watch the video...