I've used sli twice. Once with dual 6800GT's and again using a 7950GX2. Performance with both systems was great...for their time. The reality, though, is that there are single slot solutions that are truly badass cards that are already putting the bottleneck back onto the current crop of CPU's.
I'm using an 8800GTS 512 right now and I love it. If I were building new, I'd get a GTX280 period, but wouldn't be at all unhappy with a 4870 or maybe even a 9800GX2.
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