Yes, it does ice the cake. That makes it even more awesome. You should use the savegame scanner (search for a link to it in the forum) and check where the poison dagger is (or if there is one) in your game. Isshara's Whip is a quest reward and everyone gets it in every game.
To answer your question: I wouldn't recommend using Sprites and Lake Fairies without these two items. Without these items the only quality of those is their speed and initiative, which of course is nice, don't get me wrong, but they're supposed to be your main strikers and they just can't be it without those two weapons.
As for the other question: almost any "glass cannon" striker (ranged or melee alike) will go along perfectly with Demons as a tanking unit. But since I have no idea where you are, what level you're at, what class you play and what talents you chose I can't give you an honest and suitable recommendation about what to replace the girls with. I'd say: try it, play around with certain setups until you find one that suits your level, class, talents and playstyle.
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