What i can see, is that the 4650 will work, even if on the lowest settings; according to the specs.
I still doesnt know if it will work even if the model doesn´t is on the list.
here is a pic if you dont know what i am talking about.
sry for big pic.
EDIT: I should say, that i haven´t used "Can you run it" yet. I haven´t had a chance.