You can still use 'nHancer' if that's what you're familiar with, in conjunction with 'NVIDIA Inspector'. That's what I do.
The 'best' settings though depend on your hardware and what compromise between frame-rate and image-quality you want.
After the discussion in this thread -
http://forum.1cpublishing.eu/showthread.php?t=17557 I'm currently using (via 'NVIDIA Inspector') '8xSQ [Combined: 2x2 SS + 2x MS]', with 'Antialiasing- Transparency Supersampling' set to 'Supersampling', and with no Anisotropic filtering (or in-game mirrors on the airplanes).
These settings are definitely the best I've ever used in terms of reducing in-cockpit jaggies, and are pretty close to the best settings overall. But as I said, you'll have to tweak according to your own preferences and make up your own mind. Just make sure you have 'Antialiasing - Mode' set to 'Override any application setting' in order to force whatever antialiasing settings you choose.