The only thing that might give you trouble on W7 x64 is actually not the game but older hardware. For example older joysticks (x36 USB for example has no driver for w7 x64 anymore).
So if all your hardware is w7 compatible you're fine. And yes, I can only second the advice of not installing it to the standard programs folder. In fact I created a partition just for games and this way it's working fine.
