Well, i was able to load your save and successfully load the next level after entering the door. Here's the autosave the game made after loading 17th level.
If the game fails to load it, try to update or downgrade your video driver, including PhysX. However, i have an old 7950GT card, 182.08 driver and PhysX 8.09.04 (installed by 1.1 patch?) here at work. In addition, i have patched '505 games' version, not the patched Aspyr version of the game you have (they should be the same, though).
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