You usually need to approach your target from a 90 degree angle. So for example one of the map guardians on Anchor island can be kited away relatively easily the other, for me anyway, is impossible because you have to approach through such a narrow channel.(The quality of your mouse IMHO has nothing to do with it. I'm running KB:AP on an old Acer 2.4G P4 with 1G RAM and a crap mouse on minimum settings and it's all good! However if anyone has successfully kited away both map guardians on Anchor with or because of a better setup, then i guess i'll have to eat my hat!)
Approach at 90 degrees, close enough to the target to make it move/alert but far enough to avoid it's strike. Immediately it starts moving, hit the space bar to pause and quick save! Then try to move forward and in the desired direction away without letting your target lose interest. If this happens, reload to the quick save that first got your target interested and try again... (You know the target has lost interest if you see the ?? over it)
It's as/not as simple as that.
(Note: I found that while the map guardian on Anchor was impossible, on Elona between the two castles where you also only have a straight on approach, if the map guardian was an Ent it was quite easy but a Unicorn was impossible..)
BTW Blue.... If you're playing mage on impossible and willing to sacrifice 2~3 days at the start, you can kite to at least Verona then Tekron, Dersu or Elona and possibly Shettera!