I did...
Funny thing is that some items can be used to get spells/items... Like the body part bag you get from Zombie Noric.
And there are some class-specific events too. For example after bonding with the Turtle, my Mage could write down two spells into scrolls - that didn't happen with my Paladin. Also, if you play as a Paladin, Furious Paladin will sell better stuff to you (got the Silver Sword from him).