AMD (ATI) Catalyst preview drivers 12.1 now with automatic application profiles.
 

I had problems getting my custom profile to auto-apply to IL2 untill I found out not to point the profile to il2fb.exe but to the file : java.exe in the iL2, bin folder.

Hope this help somebody.

Here is my custom profile (Ati HD5850):

3D standard settings Use custom settings
SMOOTHVISION HD:Anti-Aliasing Override application settings
Level: 8X
Samples: 8X
Filter: Box
SMOOTHVISION HD:Anisotropic Filtering Override application settings
Per-pixel samples: 16X
Morphological filtering Disabled
Tessellation AMD Optimized
Texture Filtering Quality High quality
Surface Format Optimization Enabled
Mipmap Detail Level High quality
Wait for vertical refresh Always off (Somehow kill performance greatly in my case)
Anti-Aliasing Mode Multi-sample AA
OpenGL Settings Triple buffering: Enabled

Thank you, i will give it a try.

Hey Pete, i tried your VGA settings and the game is working better now. Thank you. :)